Publications since 2012
Journals
2022
Tominaga, Y. and Nokihara, K., International Journal of Peptide Research and Therapeutics, 28, 1-4, 2022. DOI 10.1007/s10989-022-10404-2.
Investigation of the Behaviors of Molecules Exhibiting Angiogenic Actions
2020
Tominaga, Y., Kitagawa, A. and Nokihara, K., Bioorganic & Medicinal Chemistry, 28 (19), 115685,2020. DOI 10.1016/j.bmc.2020.115685
Improved design of peptides exhibiting angiogenic activities for clinical applications
2019
Kawasaki, K., Sato, A., Tominaga, Y., Suzuki, Y, Tadokoro, M., Tsukiyama, K., Nokihara, K., Oyama, T. and Zen, H., Photochemistry and Photobiology, 95,946-950, 2019. DOI:10.111/php.13079
Photo-Modification of Melanin by a Mid-Infrared Free-Electron Laser in Photochemistry and Photobiology
2018
Tominaga, Y., Usui, K., Hirata, A., Ito, H. and Nokihara, K., Bioorganic & Medicinal Chemistry, 26 (12), 3210-3216, 2018. DOI 10.1016/j.bmc.2018.04.049
Applications of a novel biodetection system to saliva using protein fingerprints with data processing
2016
Sasaki, A., Ide, S., Kawamoto, Y., Bando, T, Murata, Y., Shimura, M., Yamada, K., Hirata, A., Nokihara, K., Hirata, T., Sugiyama, H., Maeshima, K., Scientific Reports, 6,29261, 2016. DOI:10.1038/srep29261 www.nature.com/scientificreports
Telomere visualization in Tissue sections Using the Pyrrole-Imidazole Polyamide probes
Nokihara, K., Kasama, T., Tominaga, Y., Kitagawa, A., Hirata, A., Ohyama, T. and Yazawa, I., Amino Acids, 48 (11), 2491-2499, 2016; DOI 10.1007/s00726-016-2269-1 online 08 June 2016.
High throughput sequencing of cyclic peptide immobilized on a gel-type single bead
Wang, N., Hirata, A., Nokihara, K., Fukase, K., Fujimoto, Y. Biopolymers, 106, 422-429, 2016. Peptidoglycan microarray as a novel tool to explore protein-ligand recognition
2015
Ohashi, Y., Ohnuma, R., Naganuma, T., Ogawa, T., Naude, R., Nokihara, K. and Muramoto, K. Food Science and Technology Research, 21 (5), 695-704, 2015.
Antioxidant Properties of Tripeptides Revealed by a Comparison of Six Different Assays
Tominaga, Y., Hirata, A., and Nokihara, K., Bioorg. Med. Chem. Lett., 25, 611-615, 2015.
Recognition of a monoclonal antibody against a small molecular weight antigen by monitoring the antigen–antibody reaction using fluorescence labeled structured peptides
2014
Hirata,A., Nokihara, K., Kawamoto, Y., Bando, T., Sasaki, A., Ide, S. Maeshima, K, Kasama, T., and Sugiyama, H., J. Am. Chem. Soc., 136, 11546-11554, 2014.
Structural Evaluation of Tandem Hairpin Pyrrole–Imidazole Polyam-ides Recognizing Human Telomeres
Hirata, A. and Nokihara, K., Tetrahedron Lett., 55, 4091-4094, 2014.
Construction of peptide-vehicles, bioconjugates having modules of cancer cell surface capture and cell-penetrating peptide with anticancer agents, focusing on efficient drug delivery
Nokihara, K. Yajima,Y.,Hirata, A., Prion, 2014, 8, 1-2
Design and syntheses of peptides which induce or enhance structural changes of recombinant bovine prion protein (rbPrP) and discovery of peptides from bovine brain which accelerate structural conversions of rbPrP
2013
Hirata, A., Miyajima, M. and Nokihara, K., J. Liq. Chromatogr. Relat. Technol., 2013, 36 (20) 2960- 2967.
Separation of peptides having structures and derivatives of mimosine, a nonproteinogenic amino acid, by a novel reverse- phase HPLC column packed with wide-pore silica
Nokihara, K., Yajima, S., Hirata, A., Sogon, T, and Yasuhara, T., FEBS Lett., 587, 673-676, 2013. Characterization of peptides obtained from digests of bovine brain which accelerate structural conversions of the recombinant bovine prion protein
2012
Braun, K., Beining, M., Wiessler, M., Lammers, T., Pipkorn, R., Hennrich, U., Nokihara, K., Semmler, W., Debus, J. and Waldeck, W. Int. J. Med. Sci., 9, 339-352, 2012.
BioShuttle Mobility in Living Cells Studied with High-Resolution FCS & CLSM Methodologies
Hirata, A., Yajim, S., Yasuhara, T., Nokihara, K., Int. J. Peptide. Res. Ther., 18, 217-225, 2012.
Structural conversion rate changes of recombinant bovine prion by designed synthetic peptides
Nokihara, K, Hirata, A, Sogon, T, Ohyama, T, Amino Acids, 54, 27-36, 2012.
Preparative scale isolation, purification and derivatization of mimosine, a non-proteinogenic amino acid
Kasai, K., Hirata, A., Ohyama, T., Nokihara, K., Yokoyama, T., Mohri, S., FEBS Lett., 586, 325-329, 2012.
Novel assay with fluorescence-labelled PrP peptides for differentiating L-type atypical and classical BSEs, and scrapie
Pipkorn. R., Wiessler, M., Waldeck, W., Hennrich, U., Nokihara, K., Beining, M., Braun, K., Int. J. Med. Sci., 9, 1-10, 2012.
Improved Synthesis Strategy for Peptide Nucleic Acids (PNA) appropriate for Cell-specific Fluorescence Imaging
Proceedings
2021
Nokihara, K., Tominaga, Y., Kasama, T., Fujino, H., Kitagawa, A., Sasaki, T. and Nokihara, S., Peptide Science 2020, Matsuura, K., and Kawano, T. (Eds) pp 43-46, 2021.
Construction of the higher efficient systems, a novel larger scale-personal synthesizer, PSP-5200, and rapid characterization for large number of peptide libraries
2019
Nokihara K, Tominaga Y, Usui K, Fujino H, Wu X, Ashida S, Kondo, K, Ikegawa M, Wei M, Kitagawa A, Nokihara S, Ito H, Mihara H, Schönbach C. Peptide Science 2018, Futaki, S. and Matsuzaki, K. (Eds), pp 20-21, 2019.
Unique and innovative biodetection system using structured and labeled peptide microarrays in combination with imaging and multivalent analyses towards diagnostics not depending on bio-markers
2017
Tominaga, Y., Usui, K., Hirata, A., Kitagawa, A., Ito, H. and Nokihara, K. Peptide Science 2016: K. Akaji (Ed.) The Japanese Peptide Society, pp 131-132, 2017.
Development of Peptide Microarray to Detect the Protein in Saliva for Periodontal Disease Test
Nokihara, K., Kasama, T., Tominaga, Y, Kitagawa, A. and Hirata, A. Peptide Science 2016: K. Akaji (Ed.) The Japanese Peptide Society, pp 33-34, 2017.
Routine deconvolution method for a cyclic peptide immobilized on a gel-type single bead (OPOB) without Edman-degradation
2016
Nokihara, K., Tominaga, Kitagawa, A., Hirata, A. and Kasama, T. Peptide Science 2015, H. Hojo, T. Inazu, H. Katayama (Eds.) The Japanese Peptide Society, pp 69-72, 2016.
High throughput amino acid analysis and sequence determination by a novel system without any derivatization using a novel column and mass spectrometer
2015
Nokihara, K., Hirata, A., Tominaga, Y., Kitagawa, A., Kasama, T. Peptide Science 2014, A. Ohtaka (Ed.) The Japanese Peptide Society, pp 51-54, 2015.
Chemical syntheses of peptides consisting of pyrrole and imidazole as building blocks and mass-spectrometric elucidation of their Microheterogeneity
Hirata, A., Nokihara, K., Kawamoto, Y., Bando, T., Maeshima, K., Sasaki, A., Ide, S., Sugiyama, H. Peptide Science 2014, A. Ohtaka (Ed.) The Japanese Peptide Society, pp 73-74, 2015.
Synthesis and characterization of tandem hairpin polyamide for telomeres visualization
2014
Nokihara, K. Tominaga, Y. Ueta G. Hirata, A., Peptide Science 2013, Y. Nishiuchi and T. Teshima (Eds.) The Japanese Peptide Society (2014) pp 389-392
Recognition studies focusing on a novel bio-detection system using arrays consisting of fluorescent labeled structured peptides as capture molecules
Hirata, A., Miyajima, M., Tominaga, Y. Ueta G. Nokihara, K. Peptide Science 2013, Y. Nishiuchi and T. Teshima (Eds.) The Japanese Peptide Society (2014) pp 145-148
Comparison of Recently Developed Polymer Supports for Assembly of Structured Polyamide in Solid-phase Syntheses
2013
Mihara, H., Usui, K., Tsutsumi, H. and Nokihara, K., Peptides, Peptides Across the Pacific, pp22-23, 2013, M. Label (Ed.), Proceedings of the 23rd American Peptide Symposium
Designed Peptide Libraries for Cell Analyzing Microarrays
Nokihara, K., Pipkorn, R., Ohyama, T., Hirata, A., Miyajima, M., Ono, N., Peptide Science 2012: K. Sugimura (Ed.) The Japanese Peptide Society, pp 167-170, 2013.
Improved Coupling Methods for the Difficult Amide-Bond Formation in Solid-Phase Assembly
Nokihara, K., Hirata, A., Yajima, S., Sogon, T., Miyajima, M., Fukano, K., Ohyama, T., Yasuhara, T. Peptide Science 2012: K. Sugimura (Ed.) The Japanese Peptide Society, pp 91-94, 2013.Development of a Protein Structural Conversion Assay and Discovery of Bovine Brain Derived Peptides Accelerating Structural Conversions of the Recombinant Bovine Prion Proteins
2012
Hirata, A., Kasama, T., Ohyama, T. and Nokihara, K., Peptide Science 2011: K. Sakaguchi (Ed.), The Japanese Peptide Society, pp 377-380, 2012.
Synthesis and Mass-Spectrometric Characterization of the Peptide-Vehicle, Peptide that Carry Molecules into Cells
Nokihara, K., Hirata, A., Sogon, T., Taira, Y., Ohyama, T., Aoyama, H., Fujita, K., Kawabata, T. and Ishikawa, K., Peptide Science 2011: K. Sakaguchi (Ed.), The Japanese Peptide Society pp 73-76, 2012.
Studies of Bioconjugates Focusing on Drug Delivery; Peptide-Vehicles Consisting of Recognition and Cell Penetrating Peptide-Modules with Anticancer Drugs
Books in Japanese 日本語版
ペプチド医薬品のスクリーニング・安定化・製剤化技術 第1章 第7節ペプチドビーズライブラリーを用いた標的探索、 軒原清史、笠間健嗣、平田晃義、冨永祐希、北川篤、軒原駿 pp 50-58, 2017 :技術情報協会 (単行本・共著)
医療・診断をささえるペプチド科学―再生医療・DDS・診断への応用―平野義明監修 (単行本・共著) 軒原清史 第Ⅶ編 診断・イメージング 第7編 第5章 ペプチドマイクロアレイPepTenChip®システムによる検査診断pp 306-315. シーエムシー出版
バイオチップの基礎と応用―原理から最新の研究・開発動向まで―伊藤嘉浩監修 ５．糖ペプチドマイクロアレイ (単行本・共著) 軒原清史 pp 103-113. シーエムシー出版